Auxilium Pharmaceuticals Announces Top-Line Results From A Pivotal Efficacy Study Of AA4500 In Dupuytren's Disease

AuxiliumPharmaceuticals, Inc. (Nasdaq: AUXL) today reported top-line results from apivotal efficacy study of AA4500, its injectable enzyme product, inpatients with Dupuytren's Disease. The Company also announced its decisionto pursue additional sources of commercial supply for AA4500 and revisedfinancial guidance with respect to Research and Development costs andfull-year loss for 2006. [click link for full article] (Source: Infectious Diseases / Bacteria / Viruses News From Medical News Today)

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Hands across the water: clinical observations of hand therapy practices in Great Britain and Norway.

Authors: Schwartz DA The Evelyn Mackin Traveling Hand Therapist Award is a new award established in 2004 by the American Hand Therapy Foundation. This award was named in honor of Evelyn Mackin, a distinguished leader in hand therapy rehabilitation. Ms. Mackin enthusiastically endorses worldwide networking among hand therapists. She strongly believes in the value of sharing knowledge and technical skills. This award enables members of the ASHT to travel, learn new concepts or skills, and share them with the American hand therapy community. Visits to clinics in Great Britain and Norway revealed similarities and differences between European and American hand therapy practice. Clinical observations explore tendon transfer rehabilitation, cold sensitivity, sensory desensitization and re-edu...

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Auxilium Pharmaceuticals, Inc.: Auxilium Pharmaceuticals, Inc. Completes Enrollment in Two Phase III Clinical Trials of XIAFLEX(TM) for Dupuytren's Contracture

MALVERN, PA (MARKET WIRE) Auxilium Pharmaceuticals, Inc. (NASDAQ: AUXL) today announced that it has completed patient enrollment in the Company's second U.S. phase III pivotal trial (CORD I) and its Australian phase III study (CORD II) of XIAFLEX™ (clostridial collagenase for injection) for the treatment of Dupuytren's contracture. In accordance with the study design, all enrolled patients have received their first injection of either XIAFLEX or placebo. Due to the high level of interest from patients and physicians, the Company was able to exceed its enrollment targets in both studies, with greater than 300 (Source: Market Wire - Pharmaceuticals and Biotech)

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[Dupuytren's disease]

Authors: Tr�ves R Dupuytren's disease is a contracture of the hand derived from the retractile fibrosis of the palmar aponeurosis, that leads to a progressive deformity in flexion of fingers. It has been named from the French surgeon Guillaume Dupuytren (1777-1835), that described it in 1831. In this note it is sketched a short biography of Dupuytren and the main clinical features of the disease are described, underlining some particular aspects of therapy. PMID: 17013443 [PubMed - in process] (Source: Reumatismo)

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Needle aponeurotomy for Dupuytren's contracture.

CONCLUSION. For Chinese patients with Dupuytren's contracture, needle aponeurotomy is safe and effective. Long-term correction is better maintained in metacarpophalangeal than proximal interphalangeal joints (70 vs 41%). PMID: 18453667 [PubMed - in process] (Source: Journal of Orthopaedic Surgery)
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Blueberry Wheat Beer Making Kit - Pick From 6 Flavors

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Phenobarbital: Dupuytren's contracture: 3 case reports.

Page: 36 (Source: Reactions Weekly)

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